Sainte-Marie-la-Mer is a commune in the Pyrénées-Orientales department in southern France. Sainte-Marie-la-Mer is located east of Perpignan…Sainte-Marie-la-Mer is a commune in the Pyrénées-Orientales department in southern France. Sainte-Marie-la-Mer is located east of Perpignan, in the canton of Perpignan-2 and in the arrondissement of Perpignan.