Weight-loss drugs like Ozempic and Wegovy have become household names in recent years. But here's why they may not work for everyone.

Ozempic, one of the semaglutide drugs that helped stars like Elon Musk, Whoopi Goldberg, and Oprah lose weight, is said to suppress hunger. But James Corden said on his Sirius XM show, This Life of Mine, that Ozempic led him to a realization, "Nothing about my eating has anything to do with being hungry."

"I tried Ozempic, and it won’t be surprising to you when you look at me now, that it didn’t really work," the British TV star said (as transcribed by People). "I tried it for

Former late-night host James Corden has revealed he tried Ozempic for weight loss but found it ineffective. "I tried Ozempic," Corden, who recently stated he was led on by Lily Allan, recently said on his podcast This Life of Mine.