AATD is an inherited disorder whose primary consequence is life-threatening pulmonary emphysema ... "ZZ" AATD were treated with a single subcutaneous dose of WVE-006 in the study.
These codes were then used to establish occupational exposures using the ALOHA job exposure matrix. Results: The prevalence of emphysema was 2.4%, chronic obstructive bronchitis 1.8%, and COPD 3.4%.