RB Jordan Mason filled in admirably to start the year, but he was hit with a shoulder injury in Week 6 that he battled until ...

Well this isn't good. 49ers rookie Isaac Guerendo is nursing a new injury. Kyle Shanahan revealed Guerendo was held out of ...

The other running backs on the 49ers' 53-man roster are Patrick Taylor Jr. and Israel Abanikanda. Taylor is expected to get ...

The San Francisco 49ers are going to have a fourth different starting running back this season according to a report from ...

Reporting emerged earlier on Thursday noting that 49ers running back Isaac Guerendo is unlikely to play in Sunday's game ...

When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo ...

San Francisco 49ers running back Isaac Guerendo is unlikely to play in Sunday's game against the host Miami Dolphins, ESPN ...

The 49ers will have to start their fourth different running back this Sunday against the Miami Dolphins. That's because ...

Coach Kyle Shanahan said Monday that the 49ers expect Guerendo (foot/hamstring) to practice Thursday, Nick Wagoner of ESPN.com reports.

The rookie running back did not practice last week and has been officially ruled out of Sunday’s clash at Hard Rock stadium ...

The injury updates from San Francisco 49ers head coach Kyle Shanahan on Monday weren't all bad. Shanahan in a conference call ...

The San Francisco 49ers face the Miami Dolphins this weekend and the rookie running back is now a major doubt to take part.