Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...

In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...

The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et ...

To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

The time bomb of misinformation and disinformation will have exploded, taking with it our ability to think for ourselves.

The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

K Heran Darwin is at New York University Grossman School of Medicine and a regular columnist for EMBO reports.

RNA modulates transcription factor binding to DNA, though the subsequent effect on transcription remains unclear. The study ...

It is boomtime for metabolism and metabolomics research. One hundred years after Otto Warburg put metabolism at the core of ...