General Hospital ’s longest recurring actor and portrayer of matriarch Monica Quartermaine, Leslie Charleson, has died at 79. Since the show’s executive producer Frank Valentini shared the news on Sunday, fans and fellow cast members have shared their reactions to the significant loss.

Colleagues are remembering the soap opera star for her "quick wit" and presence on set. She died after a long illness.

Leslie Charleson -- who played Monica Quartermaine on the soap opera General Hospital for decades -- has died at the age of 79. Variety said she died Sunday after a long, unspecified illness. "It is with a heavy heart that I announce the passing of our dead friend and colleague Leslie Charleson,

Leslie Charleson, who played popular character Dr. Monica Quartermaine for almost 50 years on “General Hospital,” has died, the program’s executive producer announced on Sunday.

Leslie Charleson, who played cardiologist Monica Quartermaine on "General Hospital" for five decades, has died, according to the soap opera's producer. She was 79.

Leslie Charleson, who played Monica Quartermaine on the iconic soap opera for nearly five decades, from 1977 to 2023, died recently at the age of 79. Frank Valentini, executive producer of “General Hospital,” shared a statement about Charleson’s death to the show’s official Instagram account on Jan. 12.

(Gray News) – “General Hospital” announced on social media Sunday that longtime actress Leslie Charleson died. She was 79 years old. The Daytime Emmy-nominated star played Monica Quartermaine on the soap opera series for nearly 50 years.

Longtime "General Hospital" star Leslie Charleson has died at 79, the show's executive producer Frank Valentini shared in a statement.

(NEXSTAR) – Leslie Charleson, perhaps best known for playing Dr. Monica Quartermaine on TV’s “General Hospital” for five decades, has passed away. She was 79. News of Charleson’s death was announced Sunday by Frank Valentini, one of the show’s producers.

Leslie Charleson, the soap-opera legend who played Monica Quartermaine on 'General Hospital' starting in the 1970s, died Sunday. She was 79.

Charleson was one of the longest serving members of the General Hospital cast, having starred in a whopping 2,079 episodes between 1977 and 2023. She previously described the environment on set as “hostile” in those early days, noting the actress before her had been “rudely fired,” per Soap Opera Digest.