Looking at Sunday’s Arizona Cardinals at San Francisco 49ers Week 5 NFL odds, lines and trends. Here’s what you need to know.

Despite the New England Patriots' 1-3 start to the 2024 season, head coach Jerod Mayo isn't considering a quarterback change.

Head coach Kyle Shanahan indicated some schematic changes may be necessary, especially once defensive tackle Javon Hargrave ...

With Hufanga nursing an ankle issue, the 49ers turned to rookie fourth-round pick Malik Mustapha as their starter.

Reeling from a last-minute loss to the Rams, the 49ers needed a game to find themselves. New England served as a necessary ...

New England Patriots safety Kyle Dugger and offensive tackle Caedan Wallace have been ruled out of Sunday’s game against the ...

Just about everything was going the way of the San Francisco 49ers on Sunday afternoon, so much so that quarterback Brock ...

Purdy finished 15-of-27 with a touchdown and an interception, and tight end George Kittle returned to catch four passes for ...

SANTA CLARA -- Brock Purdy threw a touchdown pass, Fred Warner returned an interception for a score and the San Francisco ...

Another Sunday, another full slate of NFL action nearly in the books. And boy was the latest round of regular-season action ...

Brock Purdy threw a touchdown pass, Fred Warner returned an interception for a score and the San Francisco 49ers snapped a ...

Brock Purdy completed 15 of 27 passes for 288 yards and a touchdown Sunday to help the San Francisco 49ers end a two-game ...