San Francisco 49ers linebacker Dre Greenlaw and defensive lineman Nick Bosa are active for the team's Week 16 matchup vs. the ...

The 49ers will have their best pass rusher today. Defensive end Nick Bosa officially is active for the 49ers' Week 16 game ...

Bosa on Monday shared strong opinions about the 49ers defense and coordinator Nick Sorensen — he wants the status quo in 2025 ...

With this in mind, 49ers defensive end Nick Bosa sent a subtle message to his teammates regarding their commitment to the ...

Ruled out Friday were left tackle Trent Williams (for the fifth straight game) and running back Isaac Guerendo (hamstring, ...

Orchard Park, New York, USA; San Francisco 49ers head coach Kyle Shanahan on the field before a game against the Buffalo ...

The San Francisco 49ers released their latest injury updates headed into the team's Week 16 matchup vs. the Miami Dolphins.

San Francisco had already been eliminated from postseason contention earlier in the day after coming into the season as one ...

Kyle Shanahan said a makeshift offensive line would not affect his decision to play Brock Purdy in the upcoming game against ...

What to KnowThe 49ers officially were eliminated from playoff contention after the Washington Commanders rallied to beat the ...

The 29-17 loss to the Dolphins perfectly encapsulated the campaign: statistically strong but fundamentally rotten. On Sunday, ...

Once the season ends, the 49ers will have some brutally tough decisions to make. Quarterback Brock Purdy is up for an ...