When will Isaac Guerendo return and play? Will Isaac Guerendo be back again this season? Read the latest Isaac Guerendo ...

The 49ers lost defensive tackle Javon Hargrave early with a torn triceps. Middle linebacker Fred Warner has played with an ...

Watch the San Francisco 49ers players, staff and their families celebrate the holiday season by supporting over 100 ...

San Francisco had already been eliminated from postseason contention earlier in the day after coming into the season as one ...

NFL Week 17 odds, picks, predictions, TV channel, streaming information for Monday Night Football game between Detroit Lions ...

Matos, Jake Tonges and more San Francisco 49ers players talked holiday characters as teammates, shared their favorite festive ...

If the Vikings beat the Packers on Sunday, the Lions can clinch the NFC North with a win in Week 18 no matter what they do vs ...

The 29-17 loss to the Dolphins perfectly encapsulated the campaign: statistically strong but fundamentally rotten. On Sunday, ...

Jake Moody missed a pivotal field goal on Sunday, and no one sounded more frustrated after the game than coach Kyle Shanahan.

The Detroit Lions can move one step closer to tying up top spot in the National Football Conference when they travel to the ...

Brock Purdy had his team in position for a comeback win but came up short in the city of his childhood hero Dan Marino.