Zoledronate prevents fractures in older women when administered every 12 to 18 months, but its effects on bone density and bone turnover persist beyond 5 years. Whether infrequent zoledronate ...

Patients with human epidermal growth factor receptor 2 (HER2)–positive early breast cancer with residual invasive disease after neoadjuvant systemic therapy have a high risk of recurrence and death.

In this trial involving patients with hematologic cancers, the immune responses that were elicited were similar for adjuvanted-dose and standard-dose influenza vaccines.

An urgent health care workforce crisis is looming. In the United States, a country plagued by disparate health outcomes across its geographic regions, relative physician “deserts” (i.e ...

Zoledronate prevents fractures when given every 12 to 18 months, but its effects on bone health persist well beyond 5 years. New research findings on very infrequent zoledronate dosing in early ...

The Cass Review on gender-affirming care, which has been used to justify bans in U.S. states, transgresses medical law, policy, and practice, which puts it at odds with mainstream U.S. expert ...

A quantitative alcohol history should be recorded for all patients, because alcohol use contributes to many physical and mental disorders. A person-centered, nonjudgmental approach should be adopted.

Carpal tunnel syndrome affects 87 men and 192 women per 100,000 population worldwide. 1 Common signs include paresthesia, pain, and weakness in the median nerve distribution of the hand.

Dr. Kalen N. Wright (Emergency Medicine): A 21-year-old man with sickle cell disease was evaluated in the emergency department of this hospital after loss of consciousness resulting in a fall.

A 66-year-old woman with a history of metastatic breast cancer presented to the dermatology clinic with a 1-month history of an asymptomatic, lacy rash on her left thigh.

Panel A summarizes the conventional model of how oncogenic RAS guanosine triphosphatases (i.e., Kirsten rat sarcoma viral oncogene homologue [KRAS], neuroblastoma RAS viral oncogene homologue ...

Aortic-valve stenosis is an increasingly common clinical condition in the aging population. Population studies indicate a prevalence of up to 2.5% even among persons younger than 75 years of age ...